One Laboratory Research Technician III position is available immediately in the laboratory of Dr. Q. Jane Wang at the Department of Pharmacology and Chemical Biology, University of Pittsburgh, to study protein kinase signaling in cancer and other diseases. The areas of study include signal transduction, gene regulation, mouse genetics, drug discovery and development. This is a staff position equivalent to a lab technician. The candidate will oversee daily lab operations, maintain mouse colonies, perform routine lab procedures, and train junior fellows and students. The salary will be commensurate with skills and experience.

Key Responsibilities: Manage and maintain mouse colonies, generate genetically modified mouse models, and conduct animal experiments. Perform independent laboratory experiments, including developing experimental procedures and preparing reagents and specimens. Maintain tissue cultures and perform a variety of cell-based assays and conduct live cell imaging studies. Manage lab inventory and supply ordering. Maintain detailed, accurate, and up-to-date records and logbooks. Analyze experimental data, prepare lab reports, contribute to publications, and assist in the preparation of grant proposals. Supervise and mentor junior laboratory members, supporting the development of their technical expertise and professional growth.

Qualifications: Candidates must have experience working with animals, demonstrate proficiency in mouse colony management, and have hands-on experience with tumor xenografts and genetically engineered mouse models. Candidates must hold a B.S., M.S., or higher degree in a biology-related field and demonstrate comprehensive knowledge of mouse genetics, cell biology, signal transduction, and pharmacology.
Disclaimer: The job duties outlined in this job description include common job responsibilities for this title and level of jobs and are not intended to cover every duty. The University reserves the right to assign other duties to employees that are not listed in this job description.

Performs a variety of independent laboratory work and experiments such as determining experimental protocols and preparation of specimens and cultures. Prepares reports of findings subsequent to compilation and analyzation. Oversees specimen inventory. Develops documentation for publication; crafts manuscripts and grant proposals.

Computer work: walking from place to place; standing and sitting to perform essential tasks. Good manual dexterity.

Lifting and stacking of boxes of supplies, standing for extended periods required to fulfill workload. Light - Maximum lifting of up to 20 lbs. With frequent lifting/carrying of up to 10 lbs. or a negligible amount; significant walking or standing may be required or may involve sitting with a degree of pushing and pulling.