Description

Mentor and teach associate and senior scientists. Serve as a primary customer contact for meetings, escalations, and routine events. Perform managerial tasks for work group. Perform routine and complex organic synthesis, purification and analytical evaluation of materials as part of a process chemistry research and development team. Optimize synthetic routes to active pharmaceutical ingredients for purity, reproducibility, scalability and yield. Expected to function as the overall CMC leader for drug substance program and participate in determining future directionsof the process chemistry group.

• Mentor, teach, coach, and manage other scientists.
• Participate in determining the future direction of the group including a continuous improvement plan, expansion of group capabilities and expertise.
• Carry out multistep organic syntheses, isolation, and purification of targeted products independently. Contribute to the strategic approach used to optimize reactions, isolations and purifications.
• Proficiently conduct analysis of starting materials, reaction mixtures, intermediates and products using appropriate instrumentation.
• Independently designs and proposes new synthetic processes to produce the drug substance.
• Act as PRD leader. Identify critical questions to be answered and set priorities for the process chemistry team.
• Must be able to lead a large group of scientists from a technical perspective on a project basis.
• Maintain familiarity with applicable literature including organic chemistry and techniques.
• Full, independent identification of potential chemistry issues, generation of timelines and estimates for proposal creation.
• Full participation in setting strategy and timing needed for customer proposal requests.
• Routinely generate summaries and reports on completed experimental work for internal and external use. Oral and written presentation of experimental work for internal meetings and teleconferences with customers.
• Work to ensure teamwork and cooperation exists within the group at all times.
• Conduct laboratory operations in a safe manner. Maintain familiarity with the company's chemical hygiene plan. Exhibit safety awareness and safe work practices.
• Follow responsible actions regarding chemical disposal. Maintain compliance with all regulations at the federal, state, and local levels.
• Address routine administrative requirements in a timely fashion.
• Demonstrate effective communication skills (both written and oral). Participate in project team meetings with customers.
• Work closely with manufacturing and GMP operations to coordinate project-related equipment and activities. Assist in the transfer of processes to the manufacturing team.
• Perform other related duties as assigned.

• Expert understanding of general chemistry and organic chemistry.
• Understanding of modern organic synthesis reactions, isolations and purification procedures.
• Full understanding of common synthetic organic reaction mechanisms.
• Proficient use of all relevant analytical techniques and instrumentation such as NMR, IR, MS and HPLC.
• Expertise in laboratory glassware and organic chemistry reaction set up, isolation and purification
• Must demonstrate proficiency in synthesis and purification techniques on scales ranging from milligrams to kilograms.
• Good written and verbal communication skills
• Familiarity with computer software such as ChemDraw, Microsoft Word, PowerPoint and Excel.
• Aptitude and willingness to gain more skills & knowledge.
• Strong attention to detail and superior problem-solving skills.
• Clear and concise communication skills.
• Effectively presents ideas and concepts.
• Good presentation skills.
• Demonstrates leadership skills.
• Ability to train others effectively.
• Capable of effective mentoring.
• Leads by example.
• Good mentoring skills. 
• Basic understanding of business concepts
• Good understanding and effective participation of continuous improvement processes

PI287094233